Publications
2008
77. Das, Kalyan, Ma, L.-C., Xiao, R., Radvansky, B., Aramini, J. , Zhao, L. , Marklung, J., Kuo, R.-L., Twu, K., Arnold, E., Krug, R., Montelione, G. (2008). Proc. Natl. Acad. Sci. USA. 105:13092-13097. ÒStructural basis for suppression of a host antiviral response by influenza A virus.Ó [Free access paper]
76. Mukhopadhyay, J., Das, Kalyan, Ismail, S., Koppstein, D., Jang, M., Hudson, B., Sarafianos, S., Tuske, S., Patel, J., Jansen, R., Hšfle, G., Arnold, E., Ebright, R.H. (2008). Cell 135:295-307. ÒThe RNA Polymerase ÒSwitch RegionÓ is a Target for Inhibitors.Ó [Abstract]
75. Das, Kalyan, Bauman, J.D., Clark Jr., A.D., Frenkel,
Y.V., Lewi, P.J., Shatkin, A.J., Hughes, S.H., Arnold, E. (2008). Proc.
Natl. Acad. Sci. USA. 105:1466-1471. ÒHigh-resolution structures of HIV-1 reverse
transcriptase/TMC278 complexes: strategic flexibility explains potency against
resistance mutations.Ó [Free access paper]
[C&E News
review]
74. Shatkin, A.,
Das, Kalyan, Arnold, E. (2008). Structure 16:1601-1602. Ò3D
Jigsaw Puzzle in Rotavirus Assembly.Ó [Summary]
73. Bauman, J.D., Das, Kalyan, Ho, W.C., Baweja, M., Himmel, D.M., Clark, Jr, A.D., Boyer, P.L., Hughes, S.H., and Arnold, E. (2008). Nucleic Acid Res. 36:5083-5092. ÒCrystal engineering of HIV-1 reverse transcriptase for structure-based drug design.Õ [Free access paper]
72. Fang, C., Bauman, J.D., Das, Kalyan, Remorino, A., Arnold, E., Hochstrasser, R.M. (2008). Proc. Natl. Acad. Sci. USA. 105:1472-1477. ÒTwo-dimensional infrared spectra reveal relaxation of the nonnucleoside inhibitor TMC278 complexed with HIV-1 reverse transcriptase.Ó [Abstract]
2007
71. Das, Kalyan, Sarafianos, S.G., Clark, Jr, A.D., Boyer, P.L., Hughes, S.H., Arnold, E. (2007). J. Mol. Biol. 365:77-89. ÒCrystal Structures of Clinically Relevant Lys103Asn/Tyr181Cys Double Mutant HIV-1 Reverse Transcriptase in Complexes with ATP and Non-nucleoside Inhibitor HBY 097.Ó [Abstract]
70. Campbell, E.A., Greenwell, R., Anthony, J.R., Wang, S., Lim, L., Das, Kalyan, Sofia, H.J., Donohue, T.J. and Darst, S.A. (2007). Mol. Cell 27:793-805. ÒA Conserved Structural Module Regulates Transcriptional Responses to Diverse Stress Signals in Bacteria.Ó [Abstract]
69. Su, Y., Gallicchio, E., Das, Kalyan, Arnold, E., and Levy, R.M. (2007).