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Shen, M. M. (2007). Nodal signaling: developmental roles and regulation. Development 134, 1023-1034. Gao, H., Ouyang, X., Banach-Petrosky, W. A., Gerald, W. L., Shen, M. M., and Abate-Shen, C. (2006). Combinatorial activities of Akt and B-Raf/Erk signaling in a mouse model of androgen-independent prostate cancer. Proc. Natl. Acad. Sci. USA 103, 14477-14482. Gao, H., Ouyang, X., Banach-Petrosky, W. A., Shen, M. M., and Abate-Shen, C. (2006). Emergence of Androgen Independence at Early Stages of Prostate Cancer Progression in Nkx3.1; Pten Mice. Cancer Res. 66, 7929-7933. Chen, C., Ware, S. M., Sato, A., Houston-Hawkins, D. E., Habas, R., Matzuk, M. M., Shen, M. M., and Brown, C. W. (2006). The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo. Development 133, 319-329. Chu, J., Ding, J., Jeays-Ward, K., Price, S. M., Placzek, M., and Shen, M. M. (2005). Non-cell-autonomous role for Cripto in axial midline formation during vertebrate embryogenesis. Development 132, 5539-5551. Gao, H., Ouyang, X., Banach-Petrosky, W., Borowsky, A. D., Lin, Y., Kim, M., Lee, H., Shih, W. J., Cardiff, R. D., Shen, M. M., and Abate-Shen, C. (2005). A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis. Proc. Natl. Acad. Sci. USA 101, 17204-17209. Chen, C., and Shen, M. M. (2004). Two modes by which Lefty proteins inhibit nodal signaling. Current Biology 14, 618-624. Berman, D. M., Desai, N., Wang, X., Karhadkar, S. S., Reynon, M., Abate-Shen, C., Beachy, P. A., and Shen, M. M. (2004). Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis. Dev. Biol. 267, 387-398. Shen, M. M., and Abate-Shen, C. (2003). Roles of the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis. Dev. Dyn. 228, 767-778. Abate-Shen, C., Banach-Petrosky, W. A., Sun, X., Economides, K. D., Desai, N., Gregg, J. P., Borowsky, A. D., Cardiff, R. D., and Shen, M. M. (2003). Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases. Cancer Res. 63, 3886-3890. Iratni, R., Yan, Y.-T., Chen, C., Ding, J., Zhang, Y., Price, S. M., Reinberg, D., and Shen, M. M. (2002). Inhibition of excess Nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1. Science 298, 1996-1999. Yan, Y.-T., Liu, J.-J., Luo, Y., E, C., Haltiwanger, R. S., Abate-Shen, C., and Shen, M. M. (2002). Dual roles of Cripto as a ligand and co-receptor in the Nodal signaling pathway. Mol. Cell. Biol. 22, 4439-4449. Kim, M. J., Bhatia-Gaur, R., Banach-Petrosky, W., Desai, N., Wang, Y., Hayward, S. W., Cunha, G. R., Cardiff, R. D., Shen, M. M., and Abate-Shen, C. (2002). Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis. Cancer Res. 62, 2999-3004. Abate-Shen, C., and Shen, M. M. (2002). Mouse models of prostate carcinogenesis. Trends Genet. 18, (5) S1-S5 (online). Kim, M. J., Cardiff, R. D., Desai, N., Banach-Petrosky, W., Parsons, R., Shen, M. M., and Abate-Shen, C. (2002). Cooperativity of Nkx3.1 and Pten loss-of-function in a mouse model of prostate carcinogenesis. Proc. Natl. Acad. Sci. USA 99, 2884-2889.
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